Development of fluorescent aryltryptophans by Pd mediated cross-coupling of unprotected halotryptophans in water

Abhijeet Deb Roy ; Rebecca J. M. Goss ; Gerd K. Wagner ; Michael Winn

Chem Commun 2008, 4831-4833

A convenient and high yielding procedure for the Suzuki–Miyaura cross-coupling of unprotectedbromo- and chlorotryptophans in water provides fluorescent aryltryptophans.

Graphical abstract: Development of fluorescent aryltryptophans by Pd mediated cross-coupling of unprotected halotryptophans in water